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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEA1
All Species:
16.67
Human Site:
T857
Identified Species:
61.11
UniProt:
Q15075
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15075
NP_003557.2
1411
162466
T857
A
L
M
T
E
L
S
T
V
K
D
K
L
S
K
Chimpanzee
Pan troglodytes
XP_522610
1411
162440
T857
A
L
M
T
E
L
S
T
V
K
D
K
L
S
K
Rhesus Macaque
Macaca mulatta
XP_001104577
1411
162525
T857
A
L
M
T
E
L
S
T
V
K
E
K
L
S
K
Dog
Lupus familis
XP_532649
1514
173699
A960
T
L
M
T
E
L
S
A
T
K
E
N
F
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BL66
1411
160896
T857
A
L
L
A
E
L
S
T
T
K
E
K
L
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510589
1453
166498
S899
T
I
I
K
E
L
S
S
T
K
D
K
L
S
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786840
1618
182860
E907
Y
Q
M
T
V
V
N
E
R
V
N
N
L
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.3
85.4
N.A.
85.9
N.A.
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.7
99.3
89.4
N.A.
93.1
N.A.
N.A.
87.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
48.6
P-Site Identity:
100
100
93.3
60
N.A.
73.3
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
66.6
N.A.
86.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
15
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% D
% Glu:
0
0
0
0
86
0
0
15
0
0
43
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
15
0
0
0
0
0
86
0
72
0
0
86
% K
% Leu:
0
72
15
0
0
86
0
0
0
0
0
0
86
0
0
% L
% Met:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
15
29
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
86
15
0
0
0
0
0
86
0
% S
% Thr:
29
0
0
72
0
0
0
58
43
0
0
0
0
0
0
% T
% Val:
0
0
0
0
15
15
0
0
43
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _